ToppGene Suite

A one-stop portal for gene list enrichment analysis and candidate gene prioritization
based on functional annotations and protein interactions network

GO Biological Process
Annotations:
15,037
Genes:
18,623
Updated Oct 21, 2018
GO Cellular Component
Annotations:
1,796
Genes:
19,061
Updated Oct 21, 2018
GO Molecular Function
Annotations:
4,918
Genes:
18,661
Updated Oct 21, 2018
Human Phenotype
Annotations:
8,400
Genes:
4,707
Updated Dec 11, 2017
Mouse Phenotype
Annotations:
10,687
Genes:
9,553
Updated Oct 21, 2018
Pathways
Annotations:
3,912
BioSystems: BIOCYC
314
BioSystems: KEGG
406
BioSystems: Pathway Interaction Database
186
BioSystems: REACTOME
1,860
GenMAPP
67
MSigDB C2 BIOCARTA (v6.0)
273
PantherDB
152
Pathway Ontology
321
SMPDB
333
Genes:
12,450
Domains
Annotations:
21,899
Gene3D
861
InterPro
12,487
PROSITE
1,698
Pfam
5,698
ProDom
177
SMART
978
Genes:
18,735
Pubmed
Annotations:
832,134
Genes:
37,678
Updated Oct 21, 2018
Interactions
Annotations:
17,601
Genes:
17,601
Updated Oct 21, 2018
Cytoband
Annotations:
2,354
Genes:
34,661
TFBS
Annotations:
615
Genes:
9,770
miRNA
Annotations:
6,111
MSigDB
313
MicroRNA.org
2,200
PITA
677
TargetScan
322
miRTarbase
2,599
Genes:
72,241
Gene Families
Annotations:
940
Genes:
18,194
Coexpression
Annotations:
12,022
GeneSigDB
3,515
MSigDB C2: CGP Curated Gene Sets (v6.0)
3,396
MSigDB C6: Oncogenic Signatures (v6.0)
189
MSigDB C7: Immunologic Signatures (v6.0)
4,872
MSigDB H: Hallmark Gene Sets (v6.0)
50
Genes:
23,137
Coexpression Atlas
Annotations:
6,357
Body Map
65
FaceBase_RNAseq
399
FaceBase_ST1
187
GSE76381_ESMoleculeCountsPMLog2
50
GSE76381_EmbryoMoleculeCountsPMLog2
106
GSE76381_iPSMoleculeCountsPMLog2
48
Gudmap Mouse MOE430.2
1,962
Gudmap Mouse ST 1.0
675
Gudmap RNAseq
180
Human Protein Atlas
37
Immgen.org, GSE15907
510
LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all)
52
LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all)
88
Lungmap CCHMC
103
PCBC
772
PCBC_AltAnalyze
181
Genes:
21,700
Computational Gene Set
Annotations:
858
MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0)
427
MSigDb: C4 - CM: Cancer Modules (v6.0)
431
Genes:
10,037
Drugs
Annotations:
77,163
Broad Institute CMAP Down
6,100
Broad Institute CMAP Up
6,100
CTD
12,454
Drug Bank
3,803
Stitch
48,706
Genes:
22,841
Disease
Annotations:
27,362
Clinical Variations
4,338
DisGeNET BeFree
6,857
DisGeNET Curated
13,074
GWAS
291
OMIM
2,802
Genes:
16,205
Master Gene Info File
Updated Oct 21, 2018
Build Information
ToppGene2018-Oct-02 14:36 / #70 / be2f9e192d8b359cb4769863b182225772e9d576
Settings2017-Dec-01 16:20 / #13 / 0a3d4020dcd33e9cddb00bc886dd0e5da14c195f
Visualization2017-Nov-10 19:57 / #6 / d78d2892df555ba221e23d54cfffd21384ed031a
Utilities2018-Feb-01 16:35 / #26 / 3cb34392dedd725dab89a8bd3cc8df9bc076949f
Session2018-05-15 21:08 / #10 / 0ae448e4ea13fd7fb3cd55fbc5b8050d7806490d
2018-Oct-02 14:36 / #70 / be2f9e192d8b359cb4769863b182225772e9d576 node-p3