ToppGene Suite

A one-stop portal for gene list enrichment analysis and candidate gene prioritization
based on functional annotations and protein interactions network

GO Biological Process
Annotations:
15,093
Genes:
18,623
Updated Mar 4, 2018
GO Cellular Component
Annotations:
1,800
Genes:
19,061
Updated Mar 4, 2018
GO Molecular Function
Annotations:
4,954
Genes:
18,661
Updated Mar 4, 2018
Human Phenotype
Annotations:
8,400
Genes:
4,707
Updated Dec 11, 2017
Mouse Phenotype
Annotations:
10,388
Genes:
9,319
Updated Mar 4, 2018
Pathways
Annotations:
3,912
BioSystems: BIOCYC
314
BioSystems: KEGG
406
BioSystems: Pathway Interaction Database
186
BioSystems: REACTOME
1,860
GenMAPP
67
MSigDB C2 BIOCARTA (v6.0)
273
PantherDB
152
Pathway Ontology
321
SMPDB
333
Genes:
12,450
Domains
Annotations:
21,899
Gene3D
861
InterPro
12,487
PROSITE
1,698
Pfam
5,698
ProDom
177
SMART
978
Genes:
18,735
Pubmed
Annotations:
802,015
Genes:
36,332
Updated Mar 4, 2018
Interactions
Annotations:
17,363
Genes:
17,363
Updated Mar 4, 2018
Cytoband
Annotations:
2,354
Genes:
34,661
TFBS
Annotations:
615
Genes:
9,770
miRNA
Annotations:
4,085
MSigDB
313
MicroRNA.org
2,200
PITA
677
PicTar
178
TargetScan
249
miRTarbase
324
miRecords_TarBase
144
Genes:
19,844
Gene Families
Annotations:
940
Genes:
18,194
Coexpression
Annotations:
12,022
GeneSigDB
3,515
MSigDB C2: CGP Curated Gene Sets (v6.0)
3,396
MSigDB C6: Oncogenic Signatures (v6.0)
189
MSigDB C7: Immunologic Signatures (v6.0)
4,872
MSigDB H: Hallmark Gene Sets (v6.0)
50
Genes:
23,137
Coexpression Atlas
Annotations:
5,644
Body Map
65
Brain Map - Allen iN
184
Brain Map - Barres
114
BrainMap - Mouse Adult Brain - Linnarsson
57
FaceBase_RNAseq
399
FaceBase_ST1
187
GEO:GSE75140
20
Gudmap Mouse MOE430.2
1,962
Gudmap Mouse ST 1.0
675
Gudmap RNAseq
180
Immgen.org, GSE15907
510
Lungmap CCHMC
158
MouseAtlas
72
MouseAtlasFACS
108
PCBC
772
PCBC_AltAnalyze
181
Genes:
23,956
Computational Gene Set
Annotations:
858
MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0)
427
MSigDb: C4 - CM: Cancer Modules (v6.0)
431
Genes:
10,037
Drugs
Annotations:
77,163
Broad Institute CMAP Down
6,100
Broad Institute CMAP Up
6,100
CTD
12,454
Drug Bank
3,803
Stitch
48,706
Genes:
22,841
Disease
Annotations:
27,362
Clinical Variations
4,338
DisGeNET BeFree
6,857
DisGeNET Curated
13,074
GWAS
291
OMIM
2,802
Genes:
16,205
Master Gene Info File
Updated Mar 4, 2018
Build Information
ToppGene2018-Feb-01 16:37 / #59 / a63beae66d68edb83333408e0f0e1875f881cd41
Settings2017-Dec-01 16:20 / #13 / 0a3d4020dcd33e9cddb00bc886dd0e5da14c195f
Visualization2017-Nov-10 19:57 / #6 / d78d2892df555ba221e23d54cfffd21384ed031a
Utilities2018-Feb-01 16:35 / #26 / 3cb34392dedd725dab89a8bd3cc8df9bc076949f
Session2018-01-26 17:38 / #9 / 314a0ab92e71a7cefd662a83fcccdebd90d6c66d
2018-Feb-01 16:37 / #59 / a63beae66d68edb83333408e0f0e1875f881cd41 node-p3