ToppGene Suite

A one-stop portal for gene list enrichment analysis and candidate gene prioritization
based on functional annotations and protein interactions network

GO Biological Process
Annotations:
16,735
Genes:
20,074
Updated Jul 23, 2019
GO Cellular Component
Annotations:
2,090
Genes:
20,540
Updated Jul 23, 2019
GO Molecular Function
Annotations:
4,779
Genes:
19,177
Updated Jul 23, 2019
Human Phenotype
Annotations:
8,400
Genes:
4,707
Mouse Phenotype
Annotations:
10,862
Genes:
10,564
Updated Jul 22, 2019
Pathways
Annotations:
3,912
BioSystems: BIOCYC
314
BioSystems: KEGG
406
BioSystems: Pathway Interaction Database
186
BioSystems: REACTOME
1,860
GenMAPP
67
MSigDB C2 BIOCARTA (v6.0)
273
PantherDB
152
Pathway Ontology
321
SMPDB
333
Genes:
12,450
Domains
Annotations:
21,899
Gene3D
861
InterPro
12,487
PROSITE
1,698
Pfam
5,698
ProDom
177
SMART
978
Genes:
18,735
Pubmed
Annotations:
866,710
Genes:
37,998
Updated Jul 22, 2019
Interactions
Annotations:
18,002
Genes:
18,002
Updated Jul 22, 2019
Cytoband
Annotations:
2,354
Genes:
34,661
TFBS
Annotations:
615
Genes:
9,770
miRNA
Annotations:
6,111
MSigDB
313
MicroRNA.org
2,200
PITA
677
TargetScan
322
miRTarbase
2,599
Genes:
72,241
Gene Families
Annotations:
940
Genes:
18,194
ToppCell Atlas
Annotations:
1,184
BrainMap
760
Lungmap
141
Lungmap CCHMC
103
MouseAtlas
72
MouseAtlasFACS
108
Genes:
14,373
Coexpression
Annotations:
12,022
GeneSigDB
3,515
MSigDB C2: CGP Curated Gene Sets (v6.0)
3,396
MSigDB C6: Oncogenic Signatures (v6.0)
189
MSigDB C7: Immunologic Signatures (v6.0)
4,872
MSigDB H: Hallmark Gene Sets (v6.0)
50
Genes:
23,137
Coexpression Atlas
Annotations:
4,968
Body Map
65
FaceBase_RNAseq
399
FaceBase_ST1
187
Gudmap Mouse MOE430.2
1,962
Gudmap Mouse ST 1.0
675
Gudmap RNAseq
180
Human Protein Atlas
37
Immgen.org, GSE15907
510
PCBC
772
PCBC_AltAnalyze
181
Genes:
21,555
Computational Gene Set
Annotations:
858
MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0)
427
MSigDb: C4 - CM: Cancer Modules (v6.0)
431
Genes:
10,037
Drugs
Annotations:
77,163
Broad Institute CMAP Down
6,100
Broad Institute CMAP Up
6,100
CTD
12,454
Drug Bank
3,803
Stitch
48,706
Genes:
22,841
Disease
Annotations:
24,932
Clinical Variations
4,338
DisGeNET BeFree
7,131
DisGeNET Curated
10,370
GWAS
291
OMIM
2,802
Genes:
16,284
Master Gene Info File
Updated Jul 22, 2019
Build Information
ToppGene2019-Feb-11 20:39 / #7 / bb400efd359c0f08faa3b0d90b3bbd5a8b31df3c
Settings2018-Dec-17 21:32 / #3 / 328e53bf1eecab287d45c98a7262c85e1c7a117e
Visualization2019-Jan-16 21:42 / #1 / ac0dfc7ee8d9204193d592f1d8d372626eb9621a
Utilities2019-Feb-08 17:10 / #4 / 05afd0c7ec952bbcc4546516f8acb8022f84b32e
Session2019-01-16 21:41 / #1 / f193998539321fb9c76fdd36d75d77fae3f443ef
2019-Feb-11 20:39 / #7 / bb400efd359c0f08faa3b0d90b3bbd5a8b31df3c node-p3