ToppGene Suite

A one-stop portal for gene list enrichment analysis and candidate gene prioritization
based on functional annotations and protein interactions network

GO Biological Process
Annotations:
15,202
Genes:
18,623
Updated Oct 23, 2017
GO Cellular Component
Annotations:
1,803
Genes:
19,061
Updated Oct 23, 2017
GO Molecular Function
Annotations:
4,994
Genes:
18,661
Updated Oct 23, 2017
Human Phenotype
Annotations:
6,995
Genes:
4,707
Updated Oct 27, 2017
Mouse Phenotype
Annotations:
10,058
Genes:
9,222
Updated Oct 23, 2017
Pathways
Annotations:
3,912
BioSystems: BIOCYC
314
BioSystems: KEGG
406
BioSystems: Pathway Interaction Database
186
BioSystems: REACTOME
1,860
GenMAPP
67
MSigDB C2 BIOCARTA (v6.0)
273
PantherDB
152
Pathway Ontology
321
SMPDB
333
Genes:
12,450
Domains
Annotations:
21,899
Gene3D
861
InterPro
12,487
PROSITE
1,698
Pfam
5,698
ProDom
177
SMART
978
Genes:
18,735
Pubmed
Annotations:
780,182
Genes:
52,764
Updated Oct 23, 2017
Interactions
Annotations:
17,085
Genes:
17,085
Updated Oct 23, 2017
Cytoband
Annotations:
2,354
Genes:
34,661
TFBS
Annotations:
615
Genes:
9,770
miRNA
Annotations:
4,085
MSigDB
313
MicroRNA.org
2,200
PITA
677
PicTar
178
TargetScan
249
miRTarbase
324
miRecords_TarBase
144
Genes:
19,844
Gene Families
Annotations:
940
Genes:
18,194
Coexpression
Annotations:
12,022
GeneSigDB
3,515
MSigDB C2: CGP Curated Gene Sets (v6.0)
3,396
MSigDB C6: Oncogenic Signatures (v6.0)
189
MSigDB C7: Immunologic Signatures (v6.0)
4,872
MSigDB H: Hallmark Gene Sets (v6.0)
50
Genes:
23,137
Coexpression Atlas
Annotations:
5,451
Body Map
65
Brain Map - Allen iN
184
Brain Map - Barres
114
BrainMap - Mouse Adult Brain - Linnarsson
57
FaceBase_RNAseq
399
FaceBase_ST1
187
GEO:GSE75140
20
Gudmap Mouse MOE430.2
1,962
Gudmap Mouse ST 1.0
675
Gudmap RNAseq
180
Immgen.org, GSE15907
510
Lungmap CCHMC
112
Lungmap Mouse Single Cell (Lungmap.net)
33
PCBC
772
PCBC_AltAnalyze
181
Genes:
21,020
Computational Gene Set
Annotations:
858
MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0)
427
MSigDb: C4 - CM: Cancer Modules (v6.0)
431
Genes:
10,037
Drugs
Annotations:
80,256
Broad Institute CMAP
12,200
CTD
11,832
CTD Marker
1,729
CTD Therapeutic
1,986
Drug Bank
3,803
Stitch
48,706
Genes:
22,098
Disease
Annotations:
27,362
Clinical Variations
4,338
DisGeNET BeFree
6,857
DisGeNET Curated
13,074
GWAS
291
OMIM
2,802
Genes:
16,205
Master Gene Info File
Updated Oct 23, 2017
Build Information
ToppGene2016-Sep-12 21:01 / #20 / 0e325cf20545c5d2f36a4afab5cad223a06dd6e4
Settings2016-Aug-25 19:55 / #7 / 55ef194d3d5328d215c019ce2938ab2fcf52d15b
Visualization2016-Aug-25 20:07 / #3 / e700b87fdf466b9d813f1edeb47dff3daffabcff
Utilities2016-Aug-25 20:09 / #4 / f524beaab40426cc8138c8566dc3a313179fdc6b
Session2016-08-25 19:58 / #2 / ff5ea1e149eb253b7b7c52a8b514584ec973872a
2016-Sep-12 21:01 / #20 / 0e325cf20545c5d2f36a4afab5cad223a06dd6e4 node-p1