ToppGene Suite

A one-stop portal for gene list enrichment analysis and candidate gene prioritization
based on functional annotations and protein interactions network

GO Biological Process
Annotations:
15,314
Genes:
18,785
Updated Jan 25, 2017
GO Cellular Component
Annotations:
1,804
Genes:
19,172
Updated Jan 25, 2017
GO Molecular Function
Annotations:
5,009
Genes:
18,819
Updated Jan 25, 2017
Human Phenotype
Annotations:
5,920
Genes:
4,410
Updated Jan 25, 2017
Mouse Phenotype
Annotations:
9,627
Genes:
9,299
Updated Jan 25, 2017
Pathways
Annotations:
3,643
BioSystems: BIOCYC
319
BioSystems: KEGG
362
BioSystems: Pathway Interaction Database
186
BioSystems: REACTOME
1,400
BioSystems: WikiPathways
229
GenMAPP
67
MSigDB C2 BIOCARTA (v5.1)
274
PantherDB
152
Feb 24, 2015 Pathway Ontology
321
SMPDB
333
Genes:
10,916
Domains
Annotations:
21,899
Gene3D
861
InterPro
12,487
PROSITE
1,698
Pfam
5,698
ProDom
177
SMART
978
Genes:
18,735
Pubmed
Annotations:
1,127,595
GeneRIF
392,464
Pubmed
735,131
Genes:
51,853
Updated Jan 25, 2017
Interactions
Annotations:
16,534
Genes:
16,534
Updated Jan 25, 2017
Cytoband
Annotations:
2,354
Genes:
34,661
TFBS
Annotations:
615
Genes:
9,770
miRNA
Annotations:
4,085
MSigDB
313
MicroRNA.org
2,200
PITA
677
PicTar
178
TargetScan
249
miRTarbase
324
miRecords_TarBase
144
Genes:
19,844
Gene Families
Annotations:
940
Genes:
18,194
Coexpression
Annotations:
8,446
MSigDB C2: CGP Curated Gene Sets (v5.1)
3,392
MSigDB C6: Oncogenic Signatures (v5.1)
189
MSigDB C7: Immunologic Signatures (v5.1)
4,815
MSigDB H: Hallmark Gene Sets (v5.1)
50
Genes:
21,867
Coexpression Atlas
Annotations:
5,420
Body Map
65
Brain Map - Allen iN
184
Brain Map - Barres
114
FaceBase_RNAseq
399
FaceBase_ST1
187
Gudmap Mouse MOE430.2
1,962
Gudmap Mouse ST 1.0
675
Gudmap RNAseq
180
Immgen.org, GSE15907
510
Lungmap Mouse Single Cell (Lungmap.net)
191
PCBC
772
PCBC_AltAnalyze
181
Genes:
20,974
Computational Gene Set
Annotations:
881
MSigDb: C4 - CGN: Cancer Gene Neighborhood
427
MSigDb: C4 - CM: Cancer Modules
454
Genes:
9,399
Drugs
Annotations:
80,256
Broad Institute CMAP
12,200
Oct 9, 2014 CTD
11,832
CTD Marker
1,729
CTD Therapeutic
1,986
Drug Bank
3,803
Stitch
48,706
Genes:
22,098
Disease
Annotations:
21,952
Clinical Variations
4,338
DisGeNET BeFree
6,986
DisGeNET Curated
7,607
GWAS
291
OMIM
2,730
Genes:
16,150
Master Gene Info File
Updated Jan 25, 2017
Build Information
ToppGene2016-Sep-12 21:01 / #20 / 0e325cf20545c5d2f36a4afab5cad223a06dd6e4
Settings2016-Aug-25 19:55 / #7 / 55ef194d3d5328d215c019ce2938ab2fcf52d15b
Visualization2016-Aug-25 20:07 / #3 / e700b87fdf466b9d813f1edeb47dff3daffabcff
Utilities2016-Aug-25 20:09 / #4 / f524beaab40426cc8138c8566dc3a313179fdc6b
Session2016-08-25 19:58 / #2 / ff5ea1e149eb253b7b7c52a8b514584ec973872a
2016-Sep-12 21:01 / #20 / 0e325cf20545c5d2f36a4afab5cad223a06dd6e4 node-p2